In Vitro Fertilization or IVF is a type of Assisted Reproductive Technology (ART). This technique critically comprise of introducing a combinatorial dose of medicines and surgical procedures. In IVF, you will be on fertility drugs that would let your ovaries produce multiple eggs. Once the eggs have grown to a fully mature stage, they would then be extracted out from the body with the use of ultrasound, and subsequently would be fertilized with our partner’s sperm in the laboratory. After the fertilized eggs develop into embryos, one of them would then be placed into the uterus.
IVF is gaining popularity as the only treatment for infertility. For women in whom first-line fertility treatments have been unsuccessful, IVF may be the right choice for them. IVF is certainly the choicest option when other fertility treatments, like fertility drugs or insemination, have produced unsuccessful results. IVF, thus, is a core technique when there is risk of having a pregnancy in couples who are predisposed to any type of genetic condition. So, in such cases with the help of PGD (Pre-Implantation Genetic Diagnosis)/ PGS (Pre-Implantation Genetic Screening), couples could deliver healthy pregnancy outcomes.
Step- wise Procedure:
The IVF procedure is chiefly comprised of 8 different stages:
Step 1- Commencement of the treatment
During a regular menstrual cycle, hormones from the pituitary gland cooperate in the growth and release of an egg from a fluid-filled follicle within the ovary. While numerous follicles start growing each month, only one will become mature enough to ovulate. During an IVF cycle it is desirable for several eggs to mature at the same time with FSH injections, with a trigger injection, given to mature the developing eggs before collection.
Step 2- Stimulation of the ovaries
This stage involves stimulating the ovaries with medication to promote the growth of follicles containing eggs. The response of the ovaries is monitored with regular ultrasounds and blood tests. Our fertility coordinator would confirm your procedure time, and would let you know the exact time to administer the trigger injection which would aid the final maturation of the egg.
Step 3- Egg Retrieval
Our specialist would then execute the egg retrieval or egg “pick-up”. The fluid in the follicle is then extracted into a test tube which is further examined under a microscope to look for eggs. The procedure usually lasts for about 20 to 30 minutes, depending upon the number of follicles that might have developed.
Step 4- The Sperm
On the day of our egg retrieval procedure, our partner will be asked to produce his semen sample. The sperm sample is washed and concentrated, is then supplemented to the eggs approximately four hours post retrieval of egg.
Step 5- Fertilization
One of our embryologists will contact you to discuss fertilization outcomes and any related queries would be discussed. The fertilized eggs are then kept in the incubator for an additional 48 hours.
Our treating specialist may suggest Intracytoplasmic Sperm Injection (ICSI) as part of our treatment if the sperm quality is low (sperm count, morphology or motility).
Step 6- Embryo Development
The IVF embryos must continue to grow for two or three more days to reach the blastocyst transfer stage prior to implantation into the uterine wall (endometrium).
Step 7- Embryo Transfer
The process of Embryo transfer usually occurs two to five days post retrieval of the egg. The number of embryos to be transferred shall be dependent upon the individual circumstance, along with keeping in the mind, the quality of the embryo.
Post the transfer, some of the remaining embryos that are found to be suitable for vitrification (rapid freezing), shall be carried out, and this option is typically accessible to every patient, undergoing IVF treatment. Frozen embryos could then be employed in consequent cycles (if the first one turns out to be unsuccessful). The embryos which would witness any sign of abnormality or slower development or any kind of fragmentation due to cell breakdown would be cleared for carrying out freezing procedure.
Step 8- Pregnancy Blood Test
The pregnancy blood test is due about 14 days after the embryo transfer which would then confirm if the conception has been successful.
We do recognize that the period between the embryo transfer and pregnancy test could turn out to be an emotional roller coaster, a drive filled with anxiety and expectation. Undertaking this in care, we also render tailored compassionate care and will support to ease every step of our fertility journey.
For any queries, you are always welcome to contact our team