When one or both biological parents are already aware of the existence of a genetic abnormality, PGD involves genetic testing of an embryo for a particular gene mutation. It is possible to screen any couple with a family history of aneuploidy (abnormal chromosome number) resulting in miscarriage, birth defects, or Down Syndrome. Furthermore, PGD research can be considered in families with a history of single-gene disorders, like cystic fibrosis, sickle cell anemia, and muscular dystrophy.
- Proven inherited monogenic diseases, passed down from generation to generation;
- In one of the family children, a monogenic illness has already been identified.
The special approach is Preimplantation Genetic Diagnosis (PGD or PGT-M). If a woman or man has a gene-level disorder, the exact localization of the issue can be identified and both the chromosome and the gene level can be investigated to exclude any health issues for the unborn child.
PGD (PGT-M) is conducted out:
- Reducing the likelihood of genetic disorders;
- Checking for inherited monogenic diseases;
- With personalized design & planning of tests.